PrenaTest™ is a third generation DNAscreening test forprenatal diagnosis of Down’s syndrome, Edward’s syndrome, and Patau’s syndrome (Trisomies 21, 18, and 13) in the first trimester.

There are various ways that the physicians, tracing the course of your pregnancy, may use to check the health status of your unborn child. This website is dedicated to an absolutely safe and painless blood test that could be done at a very early stage of your pregnancy. PrenaTest™ is a contemporary third-generation DNA test that allows for determining whether you are at risk of having a baby with Down’s syndrome, Patau’s syndrome or Edward’s syndrome as early as the beginning of the 9thweek of pregnancy.

PrenaTest™ does not represent a definitive diagnosis, yet it allows for determining with maximum degree of accuracy (>99%) whether your unborn baby is at a high risk of being affected by the most common congenital genetic abnormalities.

The greatest PRO for the PrenaTest™ is that it is not an invasive test. This means that no biological material has to be taken for this test either from the placenta or from the amniotic fluid, unlike the alternative methods such as amniocentesis and chorionic villus sampling that are associated with a substantial risk of complications and even of miscarriage. Quick andstress-free, the prenatal screening test PrenaTest™ only requires taking of venous blood from the mother.

If you are interested in the PrenaTest®, please ask your attending gynaecologist as early as the first visits.Then you can contact us and we shall refer you for blood sampling to a medical centre or a laboratory that is most convenient for you to visit.

Advantages of the PrenaTest™

Safety, no stress and no risk of complications and miscarriage

Thanks to the PrenaTest™ the number of the needlessly undertaken invasive test procedures – amniocentesis and chorionic villus sampling – andthe number of miscarriages as a result of these proceduresrespectively, is constantly reducing. The statistic data show that thanks to the PrenaTest™ about 20 unnecessarily terminated pregnanciesas a result of invasive examinations could be avoided on annual basis in Bulgaria.

Diagnostic possibility at a very early stage

When performed at the very start of the third week of pregnancy, PrenaTest™ gives theexpecting parents the chance to take the right decision for them in case of positive result from the test.1.

Ultramodern technology and extra information

PrenaTest™ is a contemporary method that is constantly developing. During the first 6 months of 2013 the diagnostic scope of the test has been increased, as well as its accuracy, now exceeding 99%,and as an extra benefitit offers revealing the gender of your unborn baby as early as the beginning of the 3rd month of pregnancy..

1 Съгласно препоръките на специалистите по пренатална генетика, положителните резултати от теста трябва задължително да бъдат потвърдени чрез някой от инвазивните диагностични методи.

High degree of accuracyandvery low percentage of false positive results

PrenaTest™ detectsDown’s syndrome and Trisomies 13 and 18 with greater than 99% of accuracy, while only half of a percentage of the tests give false information forexistingcongenital disease. PrenaTest™ is an innovativeprenatal diagnostic tool that perfectly complements the classical prenatal screening examinations, such as ultrasound, fetal echocardiogram (also called 4D ultrasound) and biochemical serum screening.

Availability

Bulgaria is one of the first countries in the region, outside Western Europe, where the PrenaTest™can be performed. The network of medical centres and laboratories, where blood sample can be taken for the test, covers almost all big cities of the country. In comparison, in Bulgaria amniocentesis can be done in a limited number of hospitals, which proves to be a significant inconvenience for the pregnant women.

Quality Standard

The PrenaTest® is the only non-invasive molecular genetic blood test for the detection of Down’s syndrome, Patau’s syndrome or Edward’s syndrome, which has been assessed as being in compliance with the EU quality standards for the analytical method used, thus proven its efficiency in terms of the in-vitro diagnostics directive of the European Union.

Обработка и анализ – какво се случва в лабораторията на PrenaTest™

The PrenaTest™result

The DNA prenatal test PrenaTest™ can provide you with very useful information about your pregnancy. Yet, it is essential that you understand that this is a screening test, and not a definitive diagnosis of the health status of your unborn baby. You will not get the results from us – they will be sent to your responsible gynaecologist or specialist in genetics. They are the only persons, who can make the final diagnosis, most oftensupported by the findings of additional examinationsthat they at their discretion will refer you to perform.

The following diagnostic testscan determine with absolute certaintywhether your pregnancy is associated with Down’s syndrome, trisomy 13 and 18, or with other chromosomal abnormality. They, however, carry the risk of additional complications for the pregnancy or of miscarriage.

Amniocentesis: This is a medical procedure during which the physician inserts a fine needle in the mother’s uterus. A small amount of amniotic fluid (the fluid surrounding the baby) is extracted for analysis. The procedure is usually done when a woman is between 16 and 18 weeks pregnant and is associated with miscarriage risk of about 1%.

Chorionic villus sampling: This medical procedure is related to sampling of a small tissue amount of the exterior wall of the placenta. This tissue can then be tested for chromosomal abnormalities. It can becarried out not earlier than the 12th week of pregnancy and is associated with a miscarriage risk of about 3-5%.